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A Molecular Switch between the Outer and the Inner Vestibules of the Voltage-gated Na(+) Channel
Voltage-gated ion channels are transmembrane proteins that undergo complex conformational changes during their gating transitions. Both functional and structural data from K(+) channels suggest that extracellular and intracellular parts of the pore communicate with each other via a trajectory of int...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998134/ https://www.ncbi.nlm.nih.gov/pubmed/20926383 http://dx.doi.org/10.1074/jbc.M110.132886 |