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A Molecular Switch between the Outer and the Inner Vestibules of the Voltage-gated Na(+) Channel

Voltage-gated ion channels are transmembrane proteins that undergo complex conformational changes during their gating transitions. Both functional and structural data from K(+) channels suggest that extracellular and intracellular parts of the pore communicate with each other via a trajectory of int...

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Detalles Bibliográficos
Autores principales: Zarrabi, Touran, Cervenka, Rene, Sandtner, Walter, Lukacs, Peter, Koenig, Xaver, Hilber, Karlheinz, Mille, Markus, Lipkind, Gregory M., Fozzard, Harry A., Todt, Hannes
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998134/
https://www.ncbi.nlm.nih.gov/pubmed/20926383
http://dx.doi.org/10.1074/jbc.M110.132886