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Dynamic vs Static ABCG2 Inhibitors to Sensitize Drug Resistant Cancer Cells

Human ABCG2, a member of the ATP-binding cassette transporter superfamily, plays a key role in multidrug resistance and protecting cancer stem cells. ABCG2-knockout had no apparent adverse effect on the development, biochemistry, and life of mice. Thus, ABCG2 is an interesting and promising target f...

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Detalles Bibliográficos
Autores principales: Peng, Hui, Qi, Jing, Dong, Zizheng, Zhang, Jian-Ting
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998423/
https://www.ncbi.nlm.nih.gov/pubmed/21151870
http://dx.doi.org/10.1371/journal.pone.0015276