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Dynamic vs Static ABCG2 Inhibitors to Sensitize Drug Resistant Cancer Cells
Human ABCG2, a member of the ATP-binding cassette transporter superfamily, plays a key role in multidrug resistance and protecting cancer stem cells. ABCG2-knockout had no apparent adverse effect on the development, biochemistry, and life of mice. Thus, ABCG2 is an interesting and promising target f...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998423/ https://www.ncbi.nlm.nih.gov/pubmed/21151870 http://dx.doi.org/10.1371/journal.pone.0015276 |