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Topology of the C-Terminal Tail of HIV-1 gp41: Differential Exposure of the Kennedy Epitope on Cell and Viral Membranes

The C-terminal tail (CTT) of the HIV-1 gp41 envelope (Env) protein is increasingly recognized as an important determinant of Env structure and functional properties, including fusogenicity and antigenicity. While the CTT has been commonly referred to as the “intracytoplasmic domain” based on the ass...

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Detalles Bibliográficos
Autores principales: Steckbeck, Jonathan D., Sun, Chengqun, Sturgeon, Timothy J., Montelaro, Ronald C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998427/
https://www.ncbi.nlm.nih.gov/pubmed/21151874
http://dx.doi.org/10.1371/journal.pone.0015261