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A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans
The nuo-6 and isp-1 genes of C. elegans encode, respectively, subunits of complex I and III of the mitochondrial respiratory chain. Partial loss-of-function mutations in these genes decrease electron transport and greatly increase the longevity of C. elegans by a mechanism that is distinct from that...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998438/ https://www.ncbi.nlm.nih.gov/pubmed/21151885 http://dx.doi.org/10.1371/journal.pbio.1000556 |