Cargando…

Structure of a Classical MHC Class I Molecule That Binds “Non-Classical” Ligands

Chicken YF1 genes share a close sequence relationship with classical MHC class I loci but map outside of the core MHC region. To obtain insights into their function, we determined the structure of the YF1*7.1/β(2)-microgloblin complex by X-ray crystallography at 1.3 Å resolution. It exhibits the arc...

Descripción completa

Detalles Bibliográficos
Autores principales: Hee, Chee Seng, Gao, Song, Loll, Bernhard, Miller, Marcia M., Uchanska-Ziegler, Barbara, Daumke, Oliver, Ziegler, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998441/
https://www.ncbi.nlm.nih.gov/pubmed/21151886
http://dx.doi.org/10.1371/journal.pbio.1000557