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Projection of seasonal influenza severity from sequence and serological data

Severity of seasonal influenza A epidemics is related to the antigenic novelty of the predominant viral strains circulating each year. Support for a strong correlation between epidemic severity and antigenic drift comes from infectious challenge experiments on vaccinated animals and human volunteers...

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Detalles Bibliográficos
Autores principales: Wolf, Yuri I, Nikolskaya, Anastasia, Cherry, Joshua L., Viboud, Cecile, Koonin, Eugene, Lipman, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998708/
https://www.ncbi.nlm.nih.gov/pubmed/21152078
http://dx.doi.org/10.1371/currents.RRN1200