Functional dissection of the alphavirus capsid protease: sequence requirements for activity

BACKGROUND: The alphavirus capsid is multifunctional and plays a key role in the viral life cycle. The nucleocapsid domain is released by the self-cleavage activity of the serine protease domain within the capsid. All alphaviruses analyzed to date show this autocatalytic cleavage. Here we have analy...

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Detalles Bibliográficos
Autores principales: Thomas, Saijo, Rai, Jagdish, John, Lijo, Günther, Stephan, Drosten, Christian, Pützer, Brigitte M, Schaefer, Stephan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999604/
https://www.ncbi.nlm.nih.gov/pubmed/21087473
http://dx.doi.org/10.1186/1743-422X-7-327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999604/
https://www.ncbi.nlm.nih.gov/pubmed/21087473
http://dx.doi.org/10.1186/1743-422X-7-327

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