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Functional dissection of the alphavirus capsid protease: sequence requirements for activity
BACKGROUND: The alphavirus capsid is multifunctional and plays a key role in the viral life cycle. The nucleocapsid domain is released by the self-cleavage activity of the serine protease domain within the capsid. All alphaviruses analyzed to date show this autocatalytic cleavage. Here we have analy...
Autores principales: | Thomas, Saijo, Rai, Jagdish, John, Lijo, Günther, Stephan, Drosten, Christian, Pützer, Brigitte M, Schaefer, Stephan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999604/ https://www.ncbi.nlm.nih.gov/pubmed/21087473 http://dx.doi.org/10.1186/1743-422X-7-327 |
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