Steroid receptor coactivator 1 deficiency increases MMTV-neu mediated tumor latency and differentiation specific gene expression, decreases metastasis, and inhibits response to PPAR ligands

BACKGROUND: The peroxisome proliferator activated receptor (PPAR) subgroup of the nuclear hormone receptor superfamily is activated by a variety of natural and synthetic ligands. PPARs can heterodimerize with retinoid X receptors, which have homology to other members of the nuclear receptor superfam...

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Detalles Bibliográficos
Autores principales: Han, Ji Seung, Crowe, David L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999618/
https://www.ncbi.nlm.nih.gov/pubmed/21080969
http://dx.doi.org/10.1186/1471-2407-10-629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999618/
https://www.ncbi.nlm.nih.gov/pubmed/21080969
http://dx.doi.org/10.1186/1471-2407-10-629

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