Structure–activity relationships and the cytotoxic effects of novel diterpenoid alkaloid derivatives against A549 human lung carcinoma cells

The cytotoxicity of three alkaloids from the roots of Aconitum yesoense var. macroyesoense as well as 36 semi-synthetic C(20)-diterpenoid atisine-type alkaloid derivatives against A549 human lung carcinoma cells was examined. Ten acylated alkaloid derivatives, pseudokobusine 11-veratroate (9), 11-an...

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Detalles Bibliográficos
Autores principales: Wada, Koji, Hazawa, Masaharu, Takahashi, Kenji, Mori, Takao, Kawahara, Norio, Kashiwakura, Ikuo
Formato: Texto
Lenguaje:English
Publicado: Springer Japan 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999725/
https://www.ncbi.nlm.nih.gov/pubmed/20706796
http://dx.doi.org/10.1007/s11418-010-0452-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999725/
https://www.ncbi.nlm.nih.gov/pubmed/20706796
http://dx.doi.org/10.1007/s11418-010-0452-3

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