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Structure–activity relationships and the cytotoxic effects of novel diterpenoid alkaloid derivatives against A549 human lung carcinoma cells
The cytotoxicity of three alkaloids from the roots of Aconitum yesoense var. macroyesoense as well as 36 semi-synthetic C(20)-diterpenoid atisine-type alkaloid derivatives against A549 human lung carcinoma cells was examined. Ten acylated alkaloid derivatives, pseudokobusine 11-veratroate (9), 11-an...
Autores principales: | Wada, Koji, Hazawa, Masaharu, Takahashi, Kenji, Mori, Takao, Kawahara, Norio, Kashiwakura, Ikuo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999725/ https://www.ncbi.nlm.nih.gov/pubmed/20706796 http://dx.doi.org/10.1007/s11418-010-0452-3 |
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