Modulation of Mitochondrial Permeability Transition Pore Affects Multidrug Resistance in Human Hepatocellular Carcinoma Cells

Multidrug resistance (MDR) is a critical problem in the chemotherapy of cancers. Human hepatocellular carcinoma (HCC) responds poorly to chemotherapy owing to its potent MDR. Chemotherapeutic drugs primarily act by inducing apoptosis of cancer cells, and defects in apoptosis may result in MDR. Mitoc...

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Detalles Bibliográficos
Autores principales: Ling, Xianlong, Zhou, Yuan, Li, Shi-Wei, Yan, Bin, Wen, Lei
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2010
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999853/
https://www.ncbi.nlm.nih.gov/pubmed/21152118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999853/
https://www.ncbi.nlm.nih.gov/pubmed/21152118

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