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Structural Analysis of HIV-1 Maturation Using Cryo-Electron Tomography
HIV-1 buds form infected cells in an immature, non-infectious form. Maturation into an infectious virion requires proteolytic cleavage of the Gag polyprotein at five positions, leading to a dramatic change in virus morphology. Immature virions contain an incomplete spherical shell where Gag is arran...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999899/ https://www.ncbi.nlm.nih.gov/pubmed/21151640 http://dx.doi.org/10.1371/journal.ppat.1001215 |