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Structural Analysis of HIV-1 Maturation Using Cryo-Electron Tomography

HIV-1 buds form infected cells in an immature, non-infectious form. Maturation into an infectious virion requires proteolytic cleavage of the Gag polyprotein at five positions, leading to a dramatic change in virus morphology. Immature virions contain an incomplete spherical shell where Gag is arran...

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Detalles Bibliográficos
Autores principales:	de Marco, Alex, Müller, Barbara, Glass, Bärbel, Riches, James D., Kräusslich, Hans-Georg, Briggs, John A. G.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999899/ https://www.ncbi.nlm.nih.gov/pubmed/21151640 http://dx.doi.org/10.1371/journal.ppat.1001215

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