Cargando…

3D-QSAR and Molecular Docking Studies on Derivatives of MK-0457, GSK1070916 and SNS-314 as Inhibitors against Aurora B Kinase

Development of anticancer drugs targeting Aurora B, an important member of the serine/threonine kinases family, has been extensively focused on in recent years. In this work, by applying an integrated computational method, including comparative molecular field analysis (CoMFA), comparative molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Baidong, Li, Yan, Zhang, Huixiao, Ai, Chunzhi
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000085/
https://www.ncbi.nlm.nih.gov/pubmed/21151441
http://dx.doi.org/10.3390/ijms11114326