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Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000

Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in “Eco-Challenge” multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%)...

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Autores principales: Sejvar, James, Bancroft, Elizabeth, Winthrop, Kevin, Bettinger, Julie, Bajani, Mary, Bragg, Sandra, Shutt, Kathleen, Kaiser, Robyn, Marano, Nina, Popovic, Tanja, Tappero, Jordan, Ashford, David, Mascola, Laurene, Vugia, Duc, Perkins, Bradley, Rosenstein, Nancy
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000150/
https://www.ncbi.nlm.nih.gov/pubmed/12781010
http://dx.doi.org/10.3201/eid0906.020751
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author Sejvar, James
Bancroft, Elizabeth
Winthrop, Kevin
Bettinger, Julie
Bajani, Mary
Bragg, Sandra
Shutt, Kathleen
Kaiser, Robyn
Marano, Nina
Popovic, Tanja
Tappero, Jordan
Ashford, David
Mascola, Laurene
Vugia, Duc
Perkins, Bradley
Rosenstein, Nancy
author_facet Sejvar, James
Bancroft, Elizabeth
Winthrop, Kevin
Bettinger, Julie
Bajani, Mary
Bragg, Sandra
Shutt, Kathleen
Kaiser, Robyn
Marano, Nina
Popovic, Tanja
Tappero, Jordan
Ashford, David
Mascola, Laurene
Vugia, Duc
Perkins, Bradley
Rosenstein, Nancy
author_sort Sejvar, James
collection PubMed
description Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in “Eco-Challenge” multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis.
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spelling pubmed-30001502010-12-16 Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 Sejvar, James Bancroft, Elizabeth Winthrop, Kevin Bettinger, Julie Bajani, Mary Bragg, Sandra Shutt, Kathleen Kaiser, Robyn Marano, Nina Popovic, Tanja Tappero, Jordan Ashford, David Mascola, Laurene Vugia, Duc Perkins, Bradley Rosenstein, Nancy Emerg Infect Dis Research Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in “Eco-Challenge” multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis. Centers for Disease Control and Prevention 2003-06 /pmc/articles/PMC3000150/ /pubmed/12781010 http://dx.doi.org/10.3201/eid0906.020751 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Sejvar, James
Bancroft, Elizabeth
Winthrop, Kevin
Bettinger, Julie
Bajani, Mary
Bragg, Sandra
Shutt, Kathleen
Kaiser, Robyn
Marano, Nina
Popovic, Tanja
Tappero, Jordan
Ashford, David
Mascola, Laurene
Vugia, Duc
Perkins, Bradley
Rosenstein, Nancy
Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
title Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
title_full Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
title_fullStr Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
title_full_unstemmed Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
title_short Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
title_sort leptospirosis in “eco-challenge” athletes, malaysian borneo, 2000
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000150/
https://www.ncbi.nlm.nih.gov/pubmed/12781010
http://dx.doi.org/10.3201/eid0906.020751
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