Cargando…
Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000
Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in “Eco-Challenge” multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%)...
Autores principales: | , , , , , , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000150/ https://www.ncbi.nlm.nih.gov/pubmed/12781010 http://dx.doi.org/10.3201/eid0906.020751 |
_version_ | 1782193512282849280 |
---|---|
author | Sejvar, James Bancroft, Elizabeth Winthrop, Kevin Bettinger, Julie Bajani, Mary Bragg, Sandra Shutt, Kathleen Kaiser, Robyn Marano, Nina Popovic, Tanja Tappero, Jordan Ashford, David Mascola, Laurene Vugia, Duc Perkins, Bradley Rosenstein, Nancy |
author_facet | Sejvar, James Bancroft, Elizabeth Winthrop, Kevin Bettinger, Julie Bajani, Mary Bragg, Sandra Shutt, Kathleen Kaiser, Robyn Marano, Nina Popovic, Tanja Tappero, Jordan Ashford, David Mascola, Laurene Vugia, Duc Perkins, Bradley Rosenstein, Nancy |
author_sort | Sejvar, James |
collection | PubMed |
description | Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in “Eco-Challenge” multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis. |
format | Text |
id | pubmed-3000150 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-30001502010-12-16 Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 Sejvar, James Bancroft, Elizabeth Winthrop, Kevin Bettinger, Julie Bajani, Mary Bragg, Sandra Shutt, Kathleen Kaiser, Robyn Marano, Nina Popovic, Tanja Tappero, Jordan Ashford, David Mascola, Laurene Vugia, Duc Perkins, Bradley Rosenstein, Nancy Emerg Infect Dis Research Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in “Eco-Challenge” multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis. Centers for Disease Control and Prevention 2003-06 /pmc/articles/PMC3000150/ /pubmed/12781010 http://dx.doi.org/10.3201/eid0906.020751 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Sejvar, James Bancroft, Elizabeth Winthrop, Kevin Bettinger, Julie Bajani, Mary Bragg, Sandra Shutt, Kathleen Kaiser, Robyn Marano, Nina Popovic, Tanja Tappero, Jordan Ashford, David Mascola, Laurene Vugia, Duc Perkins, Bradley Rosenstein, Nancy Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 |
title | Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 |
title_full | Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 |
title_fullStr | Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 |
title_full_unstemmed | Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 |
title_short | Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 |
title_sort | leptospirosis in “eco-challenge” athletes, malaysian borneo, 2000 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000150/ https://www.ncbi.nlm.nih.gov/pubmed/12781010 http://dx.doi.org/10.3201/eid0906.020751 |
work_keys_str_mv | AT sejvarjames leptospirosisinecochallengeathletesmalaysianborneo2000 AT bancroftelizabeth leptospirosisinecochallengeathletesmalaysianborneo2000 AT winthropkevin leptospirosisinecochallengeathletesmalaysianborneo2000 AT bettingerjulie leptospirosisinecochallengeathletesmalaysianborneo2000 AT bajanimary leptospirosisinecochallengeathletesmalaysianborneo2000 AT braggsandra leptospirosisinecochallengeathletesmalaysianborneo2000 AT shuttkathleen leptospirosisinecochallengeathletesmalaysianborneo2000 AT kaiserrobyn leptospirosisinecochallengeathletesmalaysianborneo2000 AT maranonina leptospirosisinecochallengeathletesmalaysianborneo2000 AT popovictanja leptospirosisinecochallengeathletesmalaysianborneo2000 AT tapperojordan leptospirosisinecochallengeathletesmalaysianborneo2000 AT ashforddavid leptospirosisinecochallengeathletesmalaysianborneo2000 AT mascolalaurene leptospirosisinecochallengeathletesmalaysianborneo2000 AT vugiaduc leptospirosisinecochallengeathletesmalaysianborneo2000 AT perkinsbradley leptospirosisinecochallengeathletesmalaysianborneo2000 AT rosensteinnancy leptospirosisinecochallengeathletesmalaysianborneo2000 AT leptospirosisinecochallengeathletesmalaysianborneo2000 |