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Evidence supporting a role for N(ε)-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy

PURPOSE: Recent evidence suggests that neuroglial dysfunction and degeneration contributes to the etiology and progression of diabetic retinopathy. Advanced lipoxidation end products (ALEs) have been implicated in the pathology of various diseases, including diabetes and several neurodegenerative di...

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Detalles Bibliográficos
Autores principales: Yong, Phaik Har, Zong, Hongliang, Medina, Reinhold J., Limb, G. Astrid, Uchida, Koji, Stitt, Alan W., Curtis, Tim M.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000235/
https://www.ncbi.nlm.nih.gov/pubmed/21151599