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Molecular Interactions between Prions as Seeds and Recombinant Prion Proteins as Substrates Resemble the Biological Interspecies Barrier In Vitro

Prion diseases like Creutzfeldt-Jakob disease in humans, Scrapie in sheep or bovine spongiform encephalopathy are fatal neurodegenerative diseases, which can be of sporadic, genetic, or infectious origin. Prion diseases are transmissible between different species, however, with a variable species ba...

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Detalles Bibliográficos
Autores principales: Panza, Giannantonio, Luers, Lars, Stöhr, Jan, Nagel-Steger, Luitgard, Weiβ, Jürgen, Riesner, Detlev, Willbold, Dieter, Birkmann, Eva
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000319/
https://www.ncbi.nlm.nih.gov/pubmed/21151607
http://dx.doi.org/10.1371/journal.pone.0014283