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Transcription of AAT•ATT Triplet Repeats in Escherichia coli Is Silenced by H-NS and IS1E Transposition

BACKGROUND: The trinucleotide repeats AAT•ATT are simple DNA sequences that potentially form different types of non-B DNA secondary structures and cause genomic instabilities in vivo. METHODOLOGY AND PRINCIPAL FINDINGS: The molecular mechanism underlying the maintenance of a 24-triplet AAT•ATT repea...

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Detalles Bibliográficos
Autores principales: Pan, Xuefeng, Liao, Yuanhong, Liu, Yunmeng, Chang, Peng, Liao, Lingni, Yang, Li, Li, Hongquan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000339/
https://www.ncbi.nlm.nih.gov/pubmed/21151567
http://dx.doi.org/10.1371/journal.pone.0014271