Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

While the majority of multiexonic human genes show some evidence of alternative splicing, it is unclear what fraction of observed splice forms is functionally relevant. In this study, we examine the extent of alternative splicing in human cells using deep RNA sequencing and de novo identification of...

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Detalles Bibliográficos
Autores principales: Pickrell, Joseph K., Pai, Athma A., Gilad, Yoav, Pritchard, Jonathan K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000347/
https://www.ncbi.nlm.nih.gov/pubmed/21151575
http://dx.doi.org/10.1371/journal.pgen.1001236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000347/
https://www.ncbi.nlm.nih.gov/pubmed/21151575
http://dx.doi.org/10.1371/journal.pgen.1001236

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