Continuous and Periodic Expansion of CAG Repeats in Huntington's Disease R6/1 Mice

Huntington's disease (HD) is one of several neurodegenerative disorders caused by expansion of CAG repeats in a coding gene. Somatic CAG expansion rates in HD vary between organs, and the greatest instability is observed in the brain, correlating with neuropathology. The fundamental mechanisms...

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Detalles Bibliográficos
Autores principales: Møllersen, Linda, Rowe, Alexander D., Larsen, Elisabeth, Rognes, Torbjørn, Klungland, Arne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000365/
https://www.ncbi.nlm.nih.gov/pubmed/21170307
http://dx.doi.org/10.1371/journal.pgen.1001242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000365/
https://www.ncbi.nlm.nih.gov/pubmed/21170307
http://dx.doi.org/10.1371/journal.pgen.1001242

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