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Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial

BACKGROUND: There is currently much interest in pharmacogenetics: determining variation in genes that regulate drug effects, with a particular emphasis on improving drug safety and efficacy. The ability to determine such variation motivates the application of personalized drug therapies that utilize...

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Detalles Bibliográficos
Autores principales: French, Benjamin, Joo, Jungnam, Geller, Nancy L, Kimmel, Stephen E, Rosenberg, Yves, Anderson, Jeffrey L, Gage, Brian F, Johnson, Julie A, Ellenberg, Jonas H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000386/
https://www.ncbi.nlm.nih.gov/pubmed/21083927
http://dx.doi.org/10.1186/1745-6215-11-108