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Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial
BACKGROUND: There is currently much interest in pharmacogenetics: determining variation in genes that regulate drug effects, with a particular emphasis on improving drug safety and efficacy. The ability to determine such variation motivates the application of personalized drug therapies that utilize...
Autores principales: | French, Benjamin, Joo, Jungnam, Geller, Nancy L, Kimmel, Stephen E, Rosenberg, Yves, Anderson, Jeffrey L, Gage, Brian F, Johnson, Julie A, Ellenberg, Jonas H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000386/ https://www.ncbi.nlm.nih.gov/pubmed/21083927 http://dx.doi.org/10.1186/1745-6215-11-108 |
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