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The role of HIF-1 in up-regulating MICA expression on human renal proximal tubular epithelial cells during hypoxia/reoxygenation

BACKGROUND: Human major histocompatibility complex class I-related chain A (MICA) plays a dual role in adaptive and innate immune responses. Increasing evidence demonstrates that MICA is closely correlated with acute and chronic kidney allograft rejection. Therefore, understanding the activation mec...

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Detalles Bibliográficos
Autores principales: Luo, Lei, Lu, Jun, Wei, Liang, Long, Dan, Guo, Jia Y, Shan, Juan, Li, Fu S, Lu, Ping Y, Li, Ping Y, Feng, Li
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000391/
https://www.ncbi.nlm.nih.gov/pubmed/21092233
http://dx.doi.org/10.1186/1471-2121-11-91