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HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression

BACKGROUND: Human T-cell leukemia virus type I (HTLV-I) has efficiently adapted to its host and establishes a persistent infection characterized by low levels of viral gene expression and slow proliferation of HTLV-I infected cells over decades. We have previously found that HTLV-I p30 is a negative...

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Detalles Bibliográficos
Autores principales: Baydoun, Hicham H, Pancewicz, Joanna, Bai, XueTao, Nicot, Christophe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000403/
https://www.ncbi.nlm.nih.gov/pubmed/21092281
http://dx.doi.org/10.1186/1476-4598-9-302