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Mammalian Target of Rapamycin Signaling in the Spinal Cord Is Required for Neuronal Plasticity and Behavioral Hypersensitivity Associated With Neuropathy in the Rat
The protein kinase mammalian target of rapamycin (mTOR) regulates mRNA translation and is inhibited by rapamycin. Signaling pathways involving mTOR are implicated in physiological and pathophysiological processes. We determined the spinal effects of the rapamycin analogue cell cycle inhibitor (CCI)-...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Churchill Livingstone
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000494/ https://www.ncbi.nlm.nih.gov/pubmed/20452291 http://dx.doi.org/10.1016/j.jpain.2010.03.013 |