iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

In the nucleus of eukaryotic cells, nascent transcripts are associated with heterogeneous nuclear ribonucleoprotein (hnRNP) particles that are nucleated by hnRNP C. Despite their abundance however, it remained unclear whether these particles control pre-mRNA processing. Here, we developed individual...

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Detalles Bibliográficos
Autores principales: König, Julian, Zarnack, Kathi, Rot, Gregor, Curk, Tomaž, Kayikci, Melis, Zupan, Blaž, Turner, Daniel J., Luscombe, Nicholas M., Ule, Jernej
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000544/
https://www.ncbi.nlm.nih.gov/pubmed/20601959
http://dx.doi.org/10.1038/nsmb.1838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000544/
https://www.ncbi.nlm.nih.gov/pubmed/20601959
http://dx.doi.org/10.1038/nsmb.1838

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