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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
In the nucleus of eukaryotic cells, nascent transcripts are associated with heterogeneous nuclear ribonucleoprotein (hnRNP) particles that are nucleated by hnRNP C. Despite their abundance however, it remained unclear whether these particles control pre-mRNA processing. Here, we developed individual...
Autores principales: | König, Julian, Zarnack, Kathi, Rot, Gregor, Curk, Tomaž, Kayikci, Melis, Zupan, Blaž, Turner, Daniel J., Luscombe, Nicholas M., Ule, Jernej |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000544/ https://www.ncbi.nlm.nih.gov/pubmed/20601959 http://dx.doi.org/10.1038/nsmb.1838 |
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