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Aromatase Gene Polymorphisms Are Associated with Survival among Patients with Cardiovascular Disease in a Sex-Specific Manner

INTRODUCTION: CYP19A1 encodes aromatase, the enzyme responsible for the conversion of androgens to estrogens, and may play a role in variation in outcomes among men and women with cardiovascular disease. We sought to examine genetic variation in CYP19A1 for its potential role in sex differences in c...

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Detalles Bibliográficos
Autores principales: Beitelshees, Amber L., Johnson, Julie A., Hames, Megan L., Gong, Yan, Cooper-DeHoff, Rhonda M., Wu, Jun, Cresci, Sharon, Ma, Cynthia X., Pepine, Carl J., Province, Michael A., Spertus, John A., McLeod, Howard L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000815/
https://www.ncbi.nlm.nih.gov/pubmed/21170323
http://dx.doi.org/10.1371/journal.pone.0015180