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Kita Driven Expression of Oncogenic HRAS Leads to Early Onset and Highly Penetrant Melanoma in Zebrafish

BACKGROUND: Melanoma is the most aggressive and lethal form of skin cancer. Because of the increasing incidence and high lethality of melanoma, animal models for continuously observing melanoma formation and progression as well as for testing pharmacological agents are needed. METHODOLOGY AND PRINCI...

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Detalles Bibliográficos
Autores principales: Santoriello, Cristina, Gennaro, Elisa, Anelli, Viviana, Distel, Martin, Kelly, Amanda, Köster, Reinhard W., Hurlstone, Adam, Mione, Marina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000817/
https://www.ncbi.nlm.nih.gov/pubmed/21170325
http://dx.doi.org/10.1371/journal.pone.0015170