A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

BACKGROUND: Hereditary spastic paraplegias are a group of neurological disorders characterized by progressive distal degeneration of the longest ascending and descending axons in the spinal cord, leading to lower limb spasticity and weakness. One of the dominantly inherited forms of this disease (sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lina, Brown, Anthony
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000839/
https://www.ncbi.nlm.nih.gov/pubmed/21087519
http://dx.doi.org/10.1186/1750-1326-5-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000839/
https://www.ncbi.nlm.nih.gov/pubmed/21087519
http://dx.doi.org/10.1186/1750-1326-5-52

Ejemplares similares