Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

BACKGROUND: Advanced biliary tract carcinomas (BTCs) have poor prognosis and limited therapeutic options. Therefore, it is crucial to combine standard therapies with molecular targeting. In this study EGFR, HER2, and their molecular transducers were analysed in terms of mutations, amplifications and...

Descripción completa

Detalles Bibliográficos
Autores principales: Pignochino, Ymera, Sarotto, Ivana, Peraldo-Neia, Caterina, Penachioni, Junia Y, Cavalloni, Giuliana, Migliardi, Giorgia, Casorzo, Laura, Chiorino, Giovanna, Risio, Mauro, Bardelli, Alberto, Aglietta, Massimo, Leone, Francesco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000850/
https://www.ncbi.nlm.nih.gov/pubmed/21087480
http://dx.doi.org/10.1186/1471-2407-10-631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000850/
https://www.ncbi.nlm.nih.gov/pubmed/21087480
http://dx.doi.org/10.1186/1471-2407-10-631

Ejemplares similares