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Identification of functional clock-controlled elements involved in differential timing of Per1 and Per2 transcription
It has been proposed that robust rhythmic gene expression requires clock-controlled elements (CCEs). Transcription of Per1 was reported to be regulated by the E-box and D-box in conventional reporter assays. However, such experiments are inconclusive in terms of how the CCEs and their combinations d...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001056/ https://www.ncbi.nlm.nih.gov/pubmed/20693532 http://dx.doi.org/10.1093/nar/gkq678 |