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Identification of functional clock-controlled elements involved in differential timing of Per1 and Per2 transcription

It has been proposed that robust rhythmic gene expression requires clock-controlled elements (CCEs). Transcription of Per1 was reported to be regulated by the E-box and D-box in conventional reporter assays. However, such experiments are inconclusive in terms of how the CCEs and their combinations d...

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Detalles Bibliográficos
Autores principales: Yamajuku, Daisuke, Shibata, Yasutaka, Kitazawa, Masashi, Katakura, Toshie, Urata, Hiromi, Kojima, Tomoko, Nakata, Osamu, Hashimoto, Seiichi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001056/
https://www.ncbi.nlm.nih.gov/pubmed/20693532
http://dx.doi.org/10.1093/nar/gkq678