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Sequence-specific cleavage of RNA by Type II restriction enzymes

The ability of 223 Type II restriction endonucleases to hydrolyze RNA–DNA heteroduplex oligonucleotide substrates was assessed. Despite the significant topological and sequence asymmetry introduced when one strand of a DNA duplex is substituted by RNA we find that six restriction enzymes (AvaII, Avr...

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Detalles Bibliográficos
Autores principales: Murray, Iain A., Stickel, Shawn K., Roberts, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001074/
https://www.ncbi.nlm.nih.gov/pubmed/20702422
http://dx.doi.org/10.1093/nar/gkq702