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A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

In eukaryotes, the production of mature messenger RNA that exits the nucleus to be translated into protein in the cytoplasm requires precise and extensive modification of the nascent transcript. Any failure that compromises the integrity of an mRNA may cause its retention in the nucleus and trigger...

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Detalles Bibliográficos
Autores principales: de Almeida, Sérgio F., García-Sacristán, Ana, Custódio, Noélia, Carmo-Fonseca, Maria
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001075/
https://www.ncbi.nlm.nih.gov/pubmed/20699273
http://dx.doi.org/10.1093/nar/gkq703