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A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination
In eukaryotes, the production of mature messenger RNA that exits the nucleus to be translated into protein in the cytoplasm requires precise and extensive modification of the nascent transcript. Any failure that compromises the integrity of an mRNA may cause its retention in the nucleus and trigger...
Autores principales: | de Almeida, Sérgio F., García-Sacristán, Ana, Custódio, Noélia, Carmo-Fonseca, Maria |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001075/ https://www.ncbi.nlm.nih.gov/pubmed/20699273 http://dx.doi.org/10.1093/nar/gkq703 |
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