Anti-tumor activity of splice-switching oligonucleotides

Alternative splicing has emerged as an important target for molecular therapies. Splice-switching oligonucleotides (SSOs) modulate alternative splicing by hybridizing to pre-mRNA sequences involved in splicing and blocking access to the transcript by splicing factors. Recently, the efficacy of SSOs...

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Detalles Bibliográficos
Autores principales: Bauman, John A., Li, Shyh-Dar, Yang, Angela, Huang, Leaf, Kole, Ryszard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001088/
https://www.ncbi.nlm.nih.gov/pubmed/20719743
http://dx.doi.org/10.1093/nar/gkq731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001088/
https://www.ncbi.nlm.nih.gov/pubmed/20719743
http://dx.doi.org/10.1093/nar/gkq731

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