Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice

Ribonucleotide reductase (RNR) is the rate-limiting enzyme in deoxyribonucleoside triphosphate (dNTP) biosynthesis, with important roles in nuclear genome maintenance. RNR is also essential for maintenance of mitochondrial DNA (mtDNA) in mammals. The mechanisms regulating mtDNA copy number in mammal...

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Detalles Bibliográficos
Autores principales: Ylikallio, Emil, Page, Jennifer L., Xu, Xia, Lampinen, Milla, Bepler, Gerold, Ide, Tomomi, Tyynismaa, Henna, Weiss, Robert S., Suomalainen, Anu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001089/
https://www.ncbi.nlm.nih.gov/pubmed/20724444
http://dx.doi.org/10.1093/nar/gkq735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001089/
https://www.ncbi.nlm.nih.gov/pubmed/20724444
http://dx.doi.org/10.1093/nar/gkq735

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