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Gene repression by minimal lac loops in vivo

The inflexibility of double-stranded DNA with respect to bending and twisting is well established in vitro. Understanding apparent DNA physical properties in vivo is a greater challenge. Here, we exploit repression looping with components of the Escherichia coli lac operon to monitor DNA flexibility...

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Detalles Bibliográficos
Autores principales: Bond, Laura M., Peters, Justin P., Becker, Nicole A., Kahn, Jason D., Maher, L. James
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001091/
https://www.ncbi.nlm.nih.gov/pubmed/21149272
http://dx.doi.org/10.1093/nar/gkq755