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Optimizing the noise versus bias trade-off for Illumina whole genome expression BeadChips

Five strategies for pre-processing intensities from Illumina expression BeadChips are assessed from the point of view of precision and bias. The strategies include a popular variance stabilizing transformation and model-based background corrections that either use or ignore the control probes. Four...

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Detalles Bibliográficos
Autores principales: Shi, Wei, Oshlack, Alicia, Smyth, Gordon K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001098/
https://www.ncbi.nlm.nih.gov/pubmed/20929874
http://dx.doi.org/10.1093/nar/gkq871