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Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism

BACKGROUND: The question of how the aggregation of the neuronal protein α-synuclein contributes to neuronal toxicity in Parkinson's disease has been the subject of intensive research over the past decade. Recently, attention has shifted from the amyloid fibrils to soluble oligomeric intermediat...

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Detalles Bibliográficos
Autores principales: van Rooijen, Bart D., Claessens, Mireille M. A. E., Subramaniam, Vinod
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001441/
https://www.ncbi.nlm.nih.gov/pubmed/21179192
http://dx.doi.org/10.1371/journal.pone.0014292