Multisite Phosphorylation Provides an Effective and Flexible Mechanism for Switch-Like Protein Degradation

Phosphorylation-triggered degradation is a common strategy for elimination of regulatory proteins in many important cell signaling processes. Interesting examples include cyclin-dependent kinase inhibitors such as p27 in human and Sic1 in yeast, which play crucial roles during the G1/S transition in...

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Detalles Bibliográficos
Autores principales: Varedi K., S. Marjan, Ventura, Alejandra C., Merajver, Sofia D., Lin, Xiaoxia Nina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001445/
https://www.ncbi.nlm.nih.gov/pubmed/21179196
http://dx.doi.org/10.1371/journal.pone.0014029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001445/
https://www.ncbi.nlm.nih.gov/pubmed/21179196
http://dx.doi.org/10.1371/journal.pone.0014029

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