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Multisite Phosphorylation Provides an Effective and Flexible Mechanism for Switch-Like Protein Degradation
Phosphorylation-triggered degradation is a common strategy for elimination of regulatory proteins in many important cell signaling processes. Interesting examples include cyclin-dependent kinase inhibitors such as p27 in human and Sic1 in yeast, which play crucial roles during the G1/S transition in...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001445/ https://www.ncbi.nlm.nih.gov/pubmed/21179196 http://dx.doi.org/10.1371/journal.pone.0014029 |