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The Combined Effects of Amino Acid Substitutions and Indels on the Evolution of Structure within Protein Families

BACKGROUND: In the process of protein evolution, sequence variations within protein families can cause changes in protein structures and functions. However, structures tend to be more conserved than sequences and functions. This leads to an intriguing question: what is the evolutionary mechanism by...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Wang, Yuxiao, Wang, Lushan, Gao, Peiji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001449/
https://www.ncbi.nlm.nih.gov/pubmed/21179197
http://dx.doi.org/10.1371/journal.pone.0014316