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The Combined Effects of Amino Acid Substitutions and Indels on the Evolution of Structure within Protein Families
BACKGROUND: In the process of protein evolution, sequence variations within protein families can cause changes in protein structures and functions. However, structures tend to be more conserved than sequences and functions. This leads to an intriguing question: what is the evolutionary mechanism by...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001449/ https://www.ncbi.nlm.nih.gov/pubmed/21179197 http://dx.doi.org/10.1371/journal.pone.0014316 |