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Three Novel Downstream Promoter Elements Regulate MHC Class I Promoter Activity in Mammalian Cells

BACKGROUND: MHC class I transcription is regulated by two distinct types of regulatory pathways: 1) tissue-specific pathways that establish constitutive levels of expression within a given tissue and 2) dynamically modulated pathways that increase or decrease expression within that tissue in respons...

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Detalles Bibliográficos
Autores principales: Lee, Namhoon, Iyer, Shankar S., Mu, Jie, Weissman, Jocelyn D., Ohali, Anat, Howcroft, T. Kevin, Lewis, Brian A., Singer, Dinah S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001478/
https://www.ncbi.nlm.nih.gov/pubmed/21179443
http://dx.doi.org/10.1371/journal.pone.0015278