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Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury
BACKGROUND: Toll like receptors (TLRs) signaling pathways, including the adaptor protein Mal encoded by the TIRAP gene, play a central role in the development of acute lung injury (ALI). Recently, the TIRAP variants have been described association with susceptibility to inflammatory diseases. The ai...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001691/ https://www.ncbi.nlm.nih.gov/pubmed/21118491 http://dx.doi.org/10.1186/1471-2350-11-168 |