Presenilin Controls CBP Levels in the Adult Drosophila Central Nervous System

BACKGROUND: Dominant mutations in both human Presenilin (Psn) genes have been correlated with the formation of amyloid plaques and development of familial early-onset Alzheimer's disease (AD). However, a definitive mechanism whereby plaque formation causes the pathology of familial and sporadic...

Descripción completa

Detalles Bibliográficos
Autores principales: Boyles, Randy S., Lantz, Kathryn M., Poertner, Steven, Georges, Stephanie J., Andres, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001863/
https://www.ncbi.nlm.nih.gov/pubmed/21179466
http://dx.doi.org/10.1371/journal.pone.0014332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001863/
https://www.ncbi.nlm.nih.gov/pubmed/21179466
http://dx.doi.org/10.1371/journal.pone.0014332

Ejemplares similares