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Identification of Genes and Networks Driving Cardiovascular and Metabolic Phenotypes in a Mouse F2 Intercross

To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6J x A/J F(2) (B6AF2) cross by relating genome-wide gene expression data from adipose, kidney, and liver tissues to physiological endpoints measured in the po...

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Detalles Bibliográficos
Autores principales: Derry, Jonathan M. J., Zhong, Hua, Molony, Cliona, MacNeil, Doug, Guhathakurta, Debraj, Zhang, Bin, Mudgett, John, Small, Kersten, El Fertak, Lahcen, Guimond, Alain, Selloum, Mohammed, Zhao, Wenqing, Champy, Marie France, Monassier, Laurent, Vogt, Tom, Cully, Doris, Kasarskis, Andrew, Schadt, Eric E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001864/
https://www.ncbi.nlm.nih.gov/pubmed/21179467
http://dx.doi.org/10.1371/journal.pone.0014319