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Down-Regulation of mir-424 Contributes to the Abnormal Angiogenesis via MEK1 and Cyclin E1 in Senile Hemangioma: Its Implications to Therapy

BACKGROUND: Senile hemangioma, so-called cherry angioma, is known as the most common vascular anomalies specifically seen in the aged skin. The pathogenesis of its abnormal angiogenesis is still unclear. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we found that senile hemangioma consisted of clus...

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Detalles Bibliográficos
Autores principales: Nakashima, Taiji, Jinnin, Masatoshi, Etoh, Tomomi, Fukushima, Satoshi, Masuguchi, Shinichi, Maruo, Keishi, Inoue, Yuji, Ishihara, Tsuyoshi, Ihn, Hironobu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001869/
https://www.ncbi.nlm.nih.gov/pubmed/21179471
http://dx.doi.org/10.1371/journal.pone.0014334